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KMID : 0388219940010010053
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Journal of the Korean Rheumatism Association
1994 Volume.1 No. 1 p.53 ~ p.61
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The Clinical Significance of Nailfold Capillary Microscopic Examination in the Patients with Connective Tissue Diseases
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Abstract
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Objective :
@EN Raynaud's phenomenon is a vascular disorder characterized by reversible spasm of arteries of fingers. It is the first symptom in 70% of partients with systemic sclerosis. The more systemic involvment the worse prognosis is expected in
patients
with
systemic sclerosis. A more reliable indication of systemic sclerosis is the microvascular involvement by the disease (characteristic patterns of capilary abnormality in the nailfold). Our puroses were to evaluate the significance of the degree of
nailfold capillary avnormlitry in making the diagnosis of sclerosis, and in determining organ involvement in patients with systemic sclerosis.
@ES Methods :
@EN Twenty-six patients with Raynaud's phenomenon whose diagnosis were systemic sclerosis (10 patients), SLE( 10 patient), Rayndud's disease (6 patients) were observed for nailfold capillary abnormalities by widefield microscopy.
@ES Results :
@EN Capillary abnormalities were seen in 100% of the systemic sclerosis(10 patients), 30% of the SLE(3 patients), and 50% of the Raynaud's disease(3 patients). A significant correlation between degree of finger lesions 9r=0.718) or organ
involvement
(X2=20.4, p=0.015) and capillary abnormality class was found although a significant correlation was not found between the duration of the duration of the disease and the degree of capillary abnormality in patients with systemic sclerosis(r=0.32).
@ES Conclusions :
@EN Nilfold capillary abnormality can easily be observed and could be used as an assistive tools for the diagnosis and prediction of prognosis and extent of organ involvement in patients with Raynaud's phenomenon especially in patients with
systemic
sclerosis.
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KEYWORD
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